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PharmacoScreen Panel

Flexible choice targeting over 120 genes associated with Pharmacogenomics

Available with prescribed drugs of the corresponding diseases

Overview

The main target of PharmacoScreen Panel is the genes associated
with prescribed drugs of the corresponding diseases.

Celemics has prepared three types of panels (Standard, Epilsepsy, and Anti-Tuberculosis)
to allow for client-specific selection.
Standard
The PharmacoScreen Standard panel is designed to research organ transplant-related genes
through assessment of drug metabolism, transporters, and Parkinson's disease-related genes.
Epilepsy
The PharmacoScreen Epilepsy panel is designed for genetic researches related to anti-epileptic
drugs. Our panel is also useful for assessing an individual's genetic characteristics to accurately
prescribe relevant drugs.
Anti-tuberculosis
The main target of the PharmacoScreen Anti-tuberculosis panel is the genes
associated with a drug-induced liver injury which is an important factor for drug
development as well as precise drug prescription
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Features &
Benefits

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    Assess extensive target regions associated with pharmacogenomics
    Target over 120 genes associated with Pharmacokinetics
    and Pharmacodynamics
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    Validated panel performance
    Collaborated with 4 major university hospitals with proven clinical usage
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    Flexible panel contents
    PharmacoScreen Standard, PharmacoScreen Epilepsy,
    PharmacoScreen Antituberculosis

List Of Genes

The target genes of each PharmacoScreen Panel are listed in table below.  If the panel does not contain their specific genes of interest, customers can add those genes into Celemics' pre-set panels through our additional service. Please contact us for more information.

PharmacoScreen Panel - Standard

Pharmaco
Screen Panel
Standard
ADH1B ADH1C ALDH1A1 CES1 CES2 CYP1A1 NR1I3 CYP2A6 CYP2B6 CYP2C19 CYP2C8 CYP2C9 CYP2D6 CYP2E1
CYP2J2 CYP2R1 CYP3A4 CYP3A5 CYP4F2 CYP7A1 DPYD EPHX1 PON1 GSTM1 GSTP1 GSTT1 NAT1 NAT2
SULT1A1 TPMT UGT1A1 UGT1A4 UGT1A9 UGT1A10 UGT2B15 UGT2B7 ABCA1 ABCB1 ABCB11 ABCC2 ABCC3 ABCC4
ABCC7 ABCG1 ABCG2 SLC10A1 SLC15A1 SLC15A2 SLC19A1 SLC22A1 SLC22A2 SLC22A3 SLC22A4 SLC22A5 SLC22A6 SLC22A8
SLC22A11 SLC22A12 SLCO1A2 SLCO1B1 SLCO1B3 SLCO2B1 ACE ADRB2 BRCA1 COMT DRD2 F5 HMGCR MTHFR
NQO1 P2RY1 P2RY12 PTGIS SCN5A TYMS VDR VKORC1 ADRB1 ALOX5 APOA1 ARID5B BDNF CACNA1C
CPS1 CRHR1 DBH DRD1 EGFR ESR1 FKBP5 GLCCI1 GRK4 GRK5 G6PD HTR1A HTR2A KCNH2
LDLR MAOA NR3C2 NTRK2 PEAR1 PTGS1 PTGS2 RYR1 RYR2 SCN1A SCN2A SLC47A1 SLC47A2 SLC6A3
SLC6A4 TBXAS1 ZNF423 AHR KCNJ11 NR1I3 NR1I2 POR SOD2

PharmacoScreen Panel - Epilepsy

Pharmaco
Screen Panel
Epilepsy
ANKK1 CACNA1A CACNA1B CACNA1D CACNA1E CACNA1F CACNA1G CACNA1H CACNA1I CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4
CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 CDH13 CLCN2
EFHC1 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2
GABRG3 GABRP GABRQ GABRR1 GABRR2 GABRR3 GRIA1 GRIA2 GRIA3 GRIA4 GRIK1 GRIK2 GRIK3 GRIK4
GRIK5 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GRIN3A GRIN3B HNF4A HTR1B KCNA2 KCNB1 KCNC1 KCND3
KCNH1 KCNJ10 KCNQ2 KCNQ3 KCNT1 KCNTD7 LEPR MAOA MAOB RBFOX1 SCN1A SCN2A SCN3A SCN8A
STS TPH1 TPH2 UGT1A10 UGT1A6 UGT1A7 UGT1A9

PharmacoScreen Panel - Anti-tuberculosis

Pharmaco
Screen Panel
Anti-
Tuberculosis
ABHD5 ADA ADORA2A ALAS1 ALPK2 ANO10 ASAH1 BACH1 BAX BCL2 BTLA CARD8 CASP1 CASP3
CASP8 CASP9 CAT CCL2 CD274 CD276 CD28 CD40 CD40LG CD80 CD86 CPA6 CTLA4 CYBA
DDX10 DPP4 ENTPD1 FAHD2A FAS FASLG FBXW8 FOXP3 GCLC GCLM GGT1 GPX1 GPX3 GPX4
GSR GSS GSTA1 GSTA2 GSTA3 GSTA4 GSTA5 GSTK1 GSTM2 GSTM3 GSTM4 GSTM5 GSTO1 GSTO2
GSTT2 GSTZ1 HAVCR2 HIF1A HMOX1 HMOX2 HSPA1L ICOS ICOSLG IDO1 IDO2 IFNG IFNGR1 IFNGR2
IL10 IL10RA IL12A IL12B IL12RB1 IL12RB2 IL17A IL17RA IL18 IL18R1 IL18RAP IL1A IL1B IL1R1
IL4 IL4R IL6 IL6R KCNE3 KCNIP3 KEAP1 KSR2 LAG3 LGALS9 MAFK MIR4272 MPO NFE2L2
NLRP3 NOS1 NOS2 NOS3 NT5E PDCD1 PDCD1LG2 PLXNA4 POLD3 PROM2 PSD3 SOD1 SOD3 SRXN1
STAT3 TGFB1 TGFBR1 THSD7B TN FRSF4 TNF TNFAIP3 TNFRSF14 TNFRSF1A TNFRSF1B TNFRSF9 TNFSF10 TNFSF14
TNFSF4 TNFSF9 TRIM43 TXNRD1 USP44 VTCN1 ZNF804B

Applications

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    Drug metabolism