• Just like a chameleon utilizing its
    colored pigments and crystals to
    adapt to its surroundings,
    we proactively pioneer and adapt to
    the everchanging NGS markets with
    our cutting-edge technology to
    support our customer’s needs.

Targeted Methylation Sequencing Panel

Reveals the Methylation status of Genomic Regions

Accelerating High-quality Analysis & Compatible with a variety of sample types


Celemics’ proprietary dual probe design containing bisulfite conversion allows accurate analysis of methylation status of target genes. Celemics' methylation sequencing panel provides unparalleled performance for methylation status analysis for plasma DNA. The characteristics of our Methyl-seq panel guarantee comprehensive results for both
the clinical diagnostic and research fields.
  • Step 01

    Sample DNA

  • Step 02

    Bisulfite conversion

  • Step 03


  • Step 04

    Making Panels


Features &

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    Industry-leading capture performance
    Elaborate design considering the sequence alteration by bisulfite conversion
    Thorough comparison analysis of the sequences before and after bisulfite conversion enabling accurate detection of methylation sites
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    Compatible with all sample types
    Perform methylation analysis with gDNA and cfDNA
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    Celemics’ BI analysis service for Methyl-seq
    Celemics proprietary deduplication algorithm allows
    accurate sequencing results
    Visualized results is provided to all results from methylation sequencing panel
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    High reproducibility and concordance of clinical information
    Same methylation patterns when repeatedly tested with the same sample
    Visualized clustering result from pattern analysis showed
    high concordance with the clinical data information.


Workflow of Celemics’ Targeted methylation sequencing

Standard Workflow of Targeted Methyl-seq


Celemics Proprietary Probe Design for Methyl-seq

  • Targeted methylation sequencing is processed utilizing a bisulfite conversion process in the NGS workflow.
  • The hybridization probe and methylated adapters are designed considering the sequence alteration by bisulfite conversion
  • Only selective genes can be targeted for the analysis, allowing for cost-effective sequencing.

BI analysis for methylation sequencing

Standard Analysis Pipeline for Targeted Methyl-seq

  • Customers who are new to methylation analysis can be supported by Celemics' in-house bioinformatics software service for fast and accurate analysis.
  • Comparison between C/T panel and G/A panel allows accurate discovery of methylation patterns of CpG, CHH, and CHG regions in targeted gene


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    Cancer-related epigenetics

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    Researches for gene activation