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Celemics, Inc. has developed a NGS-based antibody sequencing platform with the aim to overcome key issues of sequencing error, short-read length and high-cost gene synthesis for further characterization. Celemics’ newly developed platform, TrueRepertoireTM will allow you to sequence scFv or Fab library, analyze the entire variable region and process >10,000 clones for a single experiment.
KEY FEATURES
Offer accurate and reliable NGS-based antibody sequencing
Identify and analyze 10,000 clones at once
Allow analysis of rare clones that were hard to find in conventional methods 
Provide physical DNAs for further characterization HOW TO PROCEED
Molecular cloning of antibody library
High-throughput Separation
Multiplexed DNA barcoding
NGS VL- VH linkage analysis
DNA retrieval for characterization !
SAMPLE QUALITY RECOMMENDATIONPlasmid DNA or amplicons containing variable light and heavy domain of antibody
- Initial or bio-panned library
- scFv or Fab format
※ Please send your inquiry to Celemics technical support team (support@celemics.com)
DELIVERY- Fully-annotated antibody sequences (DNA/Amino Acid including VL-VH linkage information) with comprehensive in silico analysis report
- Sequence-verified, error-free physical antibody DNA