Home > PRODUCT > Targeted Sequencing Kit > Somatic Mutation Cancer KitSomatic Mutation Cancer Kit
In cases of somatic and cancer related mutations, treatment success can depend on not only detecting various mutation types, but also the ability to detect rare variants. NGS(Next Generation Sequencing) and Target enrichment methodology enable deep sequencing and detection of low-frequency genetic variants with precision and accuracy.
※ Research Use Only. Not for human or animal therapeutic or diagnostic use.
A single reaction, covering various mutation types.
Celemics Somatic Mutation Cancer Panel enables users to analyze multiple variant types such as SNV, InDel, CNV, Gene Rearrangement, etc. in a single assay.
GENERAL INFORMATIONAssay Genes
Rearrangement : ALK, RET, ROS1
CNV : ERBB2, MET
SNV, InDel : APC, BRAF, EGFR, ERBB2, KRAS, MET, NRAS, PIK3CA, SMAD4, TP53
CNV : ERBB2, MET
SNV, InDel : APC, BRAF, EGFR, ERBB2, KRAS, MET, NRAS, PIK3CA, SMAD4, TP53
Variants
SNV, InDel, CNV, Gene Rearrangement
Target Region
Whole CDS region, Targeted fusion regions, CNV (62Kb)
Applicable NGS platform
Illumina HiSeq / NextSeq / MiSeq
Ion Torrent PGM, Proton
Ion Torrent PGM, Proton
PRODUCT COMPOSITIONStandard Kit
Library Preparation Kit + Adaptors and Index Primers Set + Somatic mutation Target capture reagent (Probe, Hyb. Reagent and Wash Buffers)
All-in-one Kit
Standard Kit + TopQXSEP MagBead + Streptavidin Bead
PRODUCT LIST• All-in-one Kit for Illumina
• All-in-one Kit for Proton & PGM
• Standard Kit for Illumina
• Standard Kit for Proton & PGM
※ If you want some sample, please send an e-mail to Celemics technical support team (support@celemics.com).
HOW TO PROCEED
Order
Quotation
(in 1 business day)
Payment
Shipment
SAMPLE REQUIREMENTPlease send your inquiry for any samples which do not satisfy the minimum requirements described below. Samples should be prepared according to the guide below.
A. Human genomic DNA extracted from blood, tissue, saliva
Amount
Concentration
Purity
≥ 200 ng
≥ 10 ng/ul
A260/A280 = 1.8 - 2.0
※ Fluorometric quantitation method is employed to measure the amount of sample above (ex. Qubit, PicoGreen).
B. Human genomic DNA extracted from FFPE; Formalin-Fixed Paraffin-Embedded
Please send your inquiry for FFPE experiments to Celemics technical support team (support@celemics.com).
* Important Note
- For strongly degraded templates, such as FFPE samples, Celemics recommends to submit highest possible amount.
- And sequencing result may vary according to the quality of samples applied to a test.
* Additional Note
- Genomic DNA should be eluted in pure sterile water or TE buffer.
- Research use only
TURNAROUND TIMEDomestic
2~3 Weeks
International
3~4 Weeks
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